The crossword solution for the term 'Lose Focus, With 'OUT'' is 'ZONE'. To lose focus means to become distracted and not be able to concentrate on a task. Adding the word 'OUT' implies that the distraction is so great that it causes one to completely lose focus. Therefore, the phrase 'Lose Focus, With 'OUT'' can be interpreted as being completely unable to concentrate on something due to a strong distraction.