The term 'Lose a Layer' can be solved by three different crossword solutions: SHED, PEEL, and MOLT. SHED is an informal verb meaning to get rid of something, usually in reference to clothing or other items. PEEL is a verb meaning to remove the outer layer of something, such as a fruit or vegetable. MOLT is a verb meaning to SHED feathers, fur, skin, or an outer layer in order to make room for new growth. All three words refer to the act of removing an outer layer, which is what is meant by the term 'Lose a Layer'.