The two crossword solutions for the term 'Longtime First Name in TV Talk' are Merv (4 letters) and Regis (5 letters). Merv Griffin was an American television host, musician, actor, and media mogul. He hosted his own talk show, The Merv Griffin Show, from 1965 to 1986. Regis Philbin is an American media personality, actor, and singer, best known for hosting talk and game shows, including Live with Regis and Kathie Lee, Who Wants to Be a Millionaire, and America's Got Talent. He has been a fixture on television since the 1960s.