The term 'loathsome one' can be described by three crossword solutions: WORM (4 letters), TOAD (4 letters), and OGRE (4 letters). A WORM is a small, slimy invertebrate that lives in the soil and feeds on decaying organic matter. Toads are amphibians that have dry, bumpy skin and short legs. Ogres are mythical creatures that are usually depicted as large, ugly, and brutish. All three of these creatures are often seen as unpleasant or repulsive, making them fitting solutions for the term 'loathsome one'.