Letter #22 in the crossword is 'VEE', which is a three-letter word. VEE is a term used to describe the shape of a letter, number, or symbol that looks like a 'V' with two points at the top and a straight line at the bottom. It is commonly used in mathematics and engineering to represent angles, vectors, and other geometric shapes. VEE is also used in aviation to refer to a type of maneuver in which an aircraft turns in a curved path.