The crossword solution for the term LEAD, IN 'CLUE' is PIPE. LEAD is a metal that is often used IN the construction of pipes, which are hollow tubes used to transport liquids and gases. Pipes are commonly used IN plumbing and other industrial applications. LEAD is also used IN the production of LEAD-based paint, which is used to provide a protective coating on surfaces. LEAD is also used IN the manufacture of ammunition, as it is a heavy metal that can be used to increase the weight of bullets.