The term 'Lack of Comfort' can be summarized as a feeling of UNEASE, which is a 6 letter word. This feeling of UNEASE can be caused by a variety of factors, such as physical discomfort, mental distress, or emotional insecurity. It can also be caused by external factors, such as an uncomfortable environment or a stressful situation. In any case, lack of comfort can lead to feelings of anxiety, fear, and even depression.