The term 'LA CROSSE, WI' refers to a city in the state of Wisconsin. It is located along the Mississippi River and is the county seat of La Crosse County. The city is known for its vibrant downtown area, which features a variety of shops, restaurants, and entertainment venues. It is also home to the University of Wisconsin-La Crosse, as well as several other colleges and universities. La Crosse is a popular tourist destination, offering a variety of outdoor activities such as fishing, boating, and hiking.