The La Scala opera house, located in Milan, Italy, is one of the most renowned and celebrated opera houses in the world. It was founded in 1778 and has been home to some of the greatest operatic performances ever seen. The term 'La Scala' is derived from the Italian word for staircase, which is fitting as the theatre is built around a central staircase. The five-letter crossword solution for La Scala is SCALA.