Osaka is a major city in Japan located in the Kansai region. It is the third largest city in Japan with a population of over 2.7 million people. Kobe is another large city in Japan located in the Kansai region. It is the sixth largest city in Japan with a population of over 1.5 million people. Otaru is a smaller city in Japan located in the Hokkaido region. It is a port city with a population of around 140, 000 people.