Italy's Villa d'Este is a 16th-century villa located in Tivoli, near Rome. It was built by Cardinal Ippolito II d'Este and is considered one of the most important Renaissance villas in Italy. The villa is renowned for its terraced gardens, which feature a variety of fountains, grottoes, and water features. The villa is also home to a number of artworks, including frescoes by Annibale Carracci and sculptures by Gian Lorenzo Bernini. The villa is a UNESCO World Heritage Site and is open to the public. The four-letter answer to the crossword clue is ESTE.