The crossword solution for 'Italy's Villa DESTE' is a five-letter word. The answer is 'Palladio, ' referring to the Italian architect Andrea Palladio (1508-1580). Palladio was one of the most influential figures in Western architecture, and his villas are some of the most iconic examples of Renaissance architecture. Villa DESTE is one of his most famous works, located near the town of Tivoli, Italy.