The term IT TINGLES AT TIMES can be solved by the crossword solution SPINE, which is a five-letter word. The SPINE is the central column of bones that runs from the base of the skull to the tailbone and supports the body. It is made up of 33 vertebrae and is responsible for providing support and protection for the spinal cord. It also helps with movement and balance. At times, it can tingle due to nerve damage or other medical conditions.