The term 'It's Down in the Mouth' refers to two anatomical structures located in the mouth: the UVULA (5 letters) and the TONSIL (6 letters). The UVULA is a small, fleshy projection that hangs down from the soft palate at the back of the throat. The tonsils are two oval-shaped masses of lymphatic tissue located on either side of the throat. Both the UVULA and the tonsils play an important role in the body's immune system.