The crossword solution for the term IT OPENS SESAME is ESS, which stands for Electronic Security System. An Electronic Security System is a type of security system that uses electronic components to detect and prevent unauthorized access to a building or area. It typically includes sensors, alarms, cameras, and other devices that are connected to a central control panel. The system can be used to monitor and control access to a building or area, as well as to detect and deter intruders.