The term 'It May Be Set In Stone' can be summarized by two crossword solutions: RUNE (4 letters) and EPITAPH (7 letters). A RUNE is a letter, symbol, or sign that was used in ancient times to represent a concept or an object. Runes were often used in divination and magic. An EPITAPH is a phrase or statement written in memory of a deceased person, usually inscribed on a tombstone or plaque. It is typically a short poem or phrase that expresses the feelings of the deceased's family and friends.