The term 'IT DOESN'T REACT WELL' can be solved by the five-letter word 'XENON'. XENON is a chemical element with the symbol Xe and atomic number 54. It is a colorless, odorless, tasteless noble gas that occurs in the Earth's atmosphere in trace amounts. XENON is used in some medical imaging equipment and is also used to fill some types of light bulbs and in other specialized applications. It is also used in lasers and as a general anesthetic.