The term 'is inflicted with' can be summarized as having something done to one without their consent. This could refer to a physical or emotional injury, an illness, or any other type of harm. It is often used to describe a situation in which someone has been wronged or harmed in some way. In the context of a crossword puzzle, it could refer to a clue that requires the solver to find a word or phrase that describes a situation in which someone has been wronged or harmed.