The term 'IOWA STATE LOCATION' can be solved by the four-letter word 'AMES'. AMES is a city located in the central part of the U.S. state of Iowa in Story County. It is the county seat of Story County and the home of Iowa State University, which is the largest university in the state. AMES is the principal city of the AMES, Iowa Metropolitan Statistical Area, which encompasses all of Story County. As of the 2010 census, the city population was 58, 965.