The crossword solution for the term 'IOWA STATE LOCALE' is 'AMES', which is a four-letter word. AMES is a city located in the central part of the U.S. state of Iowa. It is the county seat of Story County and is located approximately 30 miles (48 km) north of Des Moines, the state capital. AMES is the home of Iowa State University of Science and Technology, a public research university with leading Agriculture, Design, Engineering, and Veterinary Medicine colleges.