The term 'Instrument with Hammers' is referring to a PIANO, which is a five-letter word. A PIANO is a musical instrument that produces sound when its keys are pressed. It has a keyboard of 88 black and white keys and is played by pressing the keys with the fingers and thumbs of both hands. The sound is produced by hammers striking strings inside the PIANO. Pianos are used in classical, jazz, and popular music.