The term INSTRUMENT FOR YO-YO MA is a 5 letter crossword solution which is the CELLO. The CELLO is a bowed string instrument of the violin family, typically with four strings tuned in perfect fifths. It is a large instrument, held between the knees of the seated player, and played by drawing a bow across its strings. Yo-Yo Ma is a world-renowned cellist who has won 18 Grammy Awards and is considered one of the greatest cellists of all time.