The term 'insignificant one' can be used to describe someone who is small, unimportant, or powerless. This can be seen in the crossword solutions for the term, which include 'SQUIRT' (6 letters), 'NOBODY' (6 letters), 'PEANUT' (6 letters), 'TWERP' (5 letters), 'SNIP' (4 letters), 'TWIT' (4 letters), 'SPRAT' (5 letters), 'halfpint' (8 letters), and 'PIPSQUEAK' (9 letters). All of these words are used to describe someone who is insignificant or powerless.