The answer to the crossword for the term 'inhabitant of ancient Persia' is MEDE. The Medes were an ancient Iranian people who lived in the northwestern part of modern-day Iran and the northeastern part of Iraq. They were one of the most powerful nations of their time, and they established the first Iranian empire. The Medes were known for their military prowess and their skill in horsemanship. They were also renowned for their art and architecture. The Medes were eventually conquered by the Persian Empire in 550 BC.