The term INFLICTS A HEAVY BLOW ON can be summarized by the crossword solution SMITES, which is a 6-letter word. Smiting is an act of striking or hitting someone or something with great force, usually with a weapon or tool. It is often used in religious contexts to describe divine punishment, such as when God SMITES the Egyptians in the Bible. In modern usage, it is often used to describe a powerful blow or strike that causes significant damage.