The term 'in chains' is used to describe a person or thing that is restrained or confined. The term can be broken down into four crossword solutions: UNFREE (6 letters), MANACLED (8 letters), FETTERED (8 letters), and SHACKLED (8 letters). All of these words refer to the act of restraining someone or something with chains, ropes, or other binding materials. UNFREE refers to being held in captivity or bondage, while MANACLED and SHACKLED both refer to being bound with metal chains or handcuffs. FETTERED is a more general term that refers to being bound with any type of restraint.