Holy Smoke! is an exclamation of surprise or amazement. The crossword solutions for this term are EGAD (4 letters), YIPES (5 letters), INCENSE (7 letters), WOW (3 letters), YOWIE (5 letters), and PEACEPIPE (9 letters). EGAD is an expression of surprise, YIPES is an exclamation of fear or dismay, INCENSE is a fragrant smoke used in religious ceremonies, WOW is an expression of amazement, YOWIE is an exclamation of surprise, and PEACEPIPE is a ceremonial pipe used to symbolize peace.