HBO's 'Real Time with Bill Maher' is a weekly talk show hosted by comedian and political commentator Bill Maher. The show features interviews with prominent figures in politics, entertainment, and other areas of public life. The show's title is derived from the term 'real time, ' which refers to the immediacy of the show's topics and discussions. The crossword solution for the term HBO's 'Real Time with Bill Maher' is MAHER, a five-letter word.