The crossword solution for the term 'Having Limited Ability to React' is INERT, which is a five-letter word. INERT means having or showing little or no activity; sluggish and apathetic. It can also refer to a substance that is not chemically reactive. Inertia is the resistance of any physical object to a change in its state of motion or rest, or the tendency of an object to resist any change in its motion.