Have Significance can be defined as having importance or value. The term is often used to describe something that has a lasting impact or is meaningful in some way. Two crossword solutions for the term are MATTER (6 letters) and COUNT (5 letters). MATTER is defined as anything that occupies space and has mass, while COUNT is defined as to name or list one by one. Together, these two words can be used to describe something that has an important presence and is worth noting.