The term 'HANDSOME THOROUGHFARE' is a combination of two words, 'HANDSOME' and 'THOROUGHFARE'. The first word, 'HANDSOME', is an adjective that means attractive or pleasing in appearance. The second word, 'THOROUGHFARE', is a noun that refers to a wide road or street, usually one that is heavily traveled. The crossword solution for this term is 'AVENUE', which is a type of THOROUGHFARE that is typically lined with trees and other vegetation. It is often used to refer to a main road or street in a city or town.