The crossword solution for the term 'GUILTY SENSATION' is PANG. A PANG is an intense, sudden feeling of mental or emotional distress. It is often associated with feelings of guilt or regret. Pangs can be caused by a variety of things, such as a traumatic event, a difficult decision, or a personal loss. They can also be caused by a sense of responsibility or obligation. Pangs are usually short-lived, but can be powerful enough to cause physical symptoms like nausea or headaches.