Grief-stricken is a term used to describe someone who is overwhelmed with sorrow and anguish. It is often used to describe someone who has experienced a great loss or tragedy. HEARTBROKEN (11 letters) is a synonym for grief-stricken, and it implies a deep emotional pain caused by a loss or disappointment. BEREFT (6 letters) is another synonym for grief-stricken, and it implies a feeling of emptiness or desolation due to a loss or tragedy.