The term 'Great Pains' is a phrase that is used to describe the effort someone puts into something. The crossword solutions for this term are 'CARE' (4 letters) and 'agonies' (7 letters). CARE is an emotion or feeling of concern for someone or something, while agonies are intense physical or mental suffering. Both words can be used to describe the effort someone puts into something, as they both imply a great deal of effort and dedication.