Grapefruit hybrids are citrus fruits that are created by cross-breeding two different varieties of grapefruit. Two popular examples of grapefruit hybrids are the TANGELO (7 letters) and the ugli (4 letters). The TANGELO is a hybrid of a tangerine and a grapefruit, while the ugli is a hybrid of a grapefruit, an orange, and a tangerine. Both hybrids have a sweet and tart flavor, and are often used in juices, salads, and desserts.