Casa Grande, Arizona is a city located in Pinal County, Arizona. It is the third largest city in the county and is home to over 50, 000 people. The city is known for its rich history and culture, as well as its proximity to the Gila River Indian Community. The name 'CASA Grande' translates to 'big house' in Spanish, and is derived from the ruins of an ancient Hohokam Indian settlement located nearby.