The term 'Goes Up Against' can be defined by the following crossword solutions: ABUTS (5 letters), DEFIES (6 letters), Opposes (7 letters), Vies (4 letters), Battles (7 letters), Takeson (7 letters). ABUTS means to be in contact with or to border on, DEFIES means to challenge or resist authority, Opposes means to be against or to act in a contrary direction, Vies means to compete for superiority, Battles means to fight or to engage in conflict, and Takeson means to undertake or to accept as a challenge. All of these words describe the action of going up against something, whether it be a person, an idea, or a situation.