The term 'GIVE IT A REST!' can be expressed in three different crossword solutions: CEASE (5 letters), TAKEFIVE (8 letters), and ENOUGHALREADY (13 letters). CEASE is a verb meaning to stop or discontinue, while TAKEFIVE is an idiom meaning to take a break or pause. ENOUGHALREADY is another idiom meaning to stop doing something because it has gone on for too long. All three of these solutions express the idea of taking a break or stopping something that has gone on for too long.