The term 'Gem of the Ocean' can be represented by two crossword solutions: PEARL (5 letters) and Spaceshuttle (12 letters). A PEARL is a hard, round object produced within the soft tissue of a living shelled mollusk. It is an organic gemstone formed by the mollusk as a defense mechanism against a potentially threatening irritant such as a parasite inside its shell. The Spaceshuttle was a partially reusable low Earth orbital spacecraft system operated by the U.S. National Aeronautics and Space Administration (NASA) from 1981 to 2011. It carried astronauts into space and provided the main means for transporting cargo to and from the International Space Station.