The term GAMBLING CAPITAL OF THE WORLD is answered by the five-letter word MACAU. Macau is a special administrative region of China located on the western side of the Pearl River Delta. It is known for its vibrant gambling industry, which has been in operation since the 1850s. Macau is now the world's largest gambling destination, with more than 30 casinos and numerous other gaming venues. It is estimated that Macau's gambling industry generates more than $45 billion in annual revenue, making it the most profitable gambling destination in the world.