Frasier's last name is CRANE, a five letter word. Frasier is a character from the popular American sitcom 'Frasier', which aired from 1993 to 2004. The show follows the life of Dr. Frasier CRANE, a psychiatrist who moves back to his hometown of Seattle, Washington after his divorce. He lives with his father, Martin, and brother, Niles, and works as a radio psychiatrist. The show was a spin-off of the popular show 'Cheers' and was one of the most successful spin-offs in television history.