The answer to the crossword for the term 'Forties' First Lady' is Eleanor, with 7 letters. Eleanor Roosevelt was the wife of President Franklin D. Roosevelt and served as the First Lady of the United States from 1933 to 1945. She was an advocate for civil rights and a prominent figure in the women's rights movement. She was also a prolific writer and speaker, and her influence on American politics and culture during the 1940s was significant.