Florida's Key LARGO is the largest of the Florida Keys, an archipelago of islands located off the southern coast of the state. It is known for its coral reefs and marine life, as well as its many resorts and marinas. Biscayne National Park is located on the northernmost island of the Florida Keys, and is home to a variety of wildlife, including manatees, sea turtles, and dolphins. SIESTA Key is a barrier island located off the coast of Sarasota, Florida, and is known for its white sand beaches and crystal-clear waters.