The term 'First-Generation Japanese-American' refers to the Issei, a group of immigrants who were the first generation of Japanese people to settle in the United States. The Issei were born in Japan and immigrated to the United States during the late 19th century and early 20th century. They faced many challenges as they adjusted to life in a new country, including discrimination and language barriers. Despite these difficulties, the Issei made significant contributions to American society, particularly in the areas of agriculture, business, and culture.