The term 'FIRST ANIMAL SHELTER' can be solved by the crossword clue 'ARK' (3 letters). An ARK is a large boat or ship, most famously known from the biblical story of Noah's ARK. In modern times, an ARK is often used to refer to a place of refuge or shelter, particularly for animals. The first animal shelter was established in 1824 in England, and since then, many more have been created around the world.