The Environmental Protection Agency (EPA) Word for this crossword puzzle is 'TOXIC'. The EPA is a government agency that works to protect human health and the environment by creating and enforcing regulations based on laws passed by Congress. TOXIC substances are those that can cause harm to living organisms, including humans, and can be found in air, water, soil, and food. The EPA works to reduce the amount of TOXIC substances in the environment by setting standards and regulations for their use and disposal.