The two crossword solutions for the term 'Enemy of Spider-Man' are Electro and Green Goblin. Electro is a supervillain who first appeared in Marvel Comics in 1964. He has the ability to control electricity and has been a long-time enemy of Spider-Man. Green Goblin is another supervillain who first appeared in Marvel Comics in 1964. He is a genius inventor and has a variety of weapons at his disposal, making him a formidable foe for Spider-Man.