The crossword solution for the term 'E. African Nation' is ETH, which is the two-letter country code for Ethiopia. Ethiopia is a country located in the Horn of Africa and is the second-most populous nation in Africa. It is bordered by Eritrea to the north, Djibouti and Somalia to the east, Sudan and South Sudan to the west, and Kenya to the south. Ethiopia has a rich cultural history and is home to many ancient monuments and archaeological sites. It is also known for its diverse wildlife and landscapes.