Down State is a term used to refer to the lower part of the United States, typically referring to the states located in the south. The two crossword solutions for this term are WOE (3 letters) and DESPAIR (7 letters). WOE is an expression of grief or sorrow, while DESPAIR is a feeling of hopelessness and helplessness. Both words are often used to describe the feelings associated with Down State, which can be seen as a region of sadness and DESPAIR.