The term 'Do with a Pick, Maybe' can be solved by the crossword solutions AFRO (4 letters) and FRO (3 letters). AFRO stands for 'African-American Freedom Riders Organization', which was a civil rights organization founded in 1961. The organization's mission was to challenge racial segregation on public transportation. FRO stands for 'Freedom Riders Organization', which was a civil rights organization founded in 1965. The organization's mission was to end segregation in public transportation and to promote racial equality.